Hepatitis B virus X protein and C/EBPs cooperate in the activation of SREBP-1a transcription
【摘要】:正BACKGROUND AIMS HBx is well-known to be a multifunctional protein which is an important regulator of hepatic steatosis observed in patients with hepatitis B virus.Sterol regulatory element binding protein-1a(SREBP-1a) is a potent activator of genes involved in the synthesis of cholesterol,fatty acids and triacylglycerol.Our previously study showed that HBx
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