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Carvacrol Attenuates Diabetic Cardiomyopathy by Enhancing PI3K/AKT Pathway in STZ-induced Type 1 Diabetic C57BL/6J Mice

Hou Ning  Mai Yunpei  Wenliang Chen  JiANDong Luo  
【摘要】:正Background:Carvacrol(CAR),a monoterpenic phenol that occurs in many essential oils of the family Labiatae including Origanum,Satureja,Thymbra,Thymus,and Corydothymus species,possess a wide variety of pharmacological properties including antioxidant and anti-inflammatory potential.This present study was designed to investigate the cardiac protective effect of CAR on diabetic cardiomyopathy in STZ-induced type 1 diabetic mice and explore its potential molecular mechanism.

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