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Evaluation of anti-aging activities of various ginsenosides by typeⅠprocollagen synthesis and expression of MMP-1

Ho Sik Rho  Myung Hun Yeom  Duck Hee Kim  Han Gon Kim  Jaeho Yeon  
【摘要】:正Anti-aging activities of various ginsenosides were evaluated by typeⅠprocollagen synthesis and the expression of MMP-1.In typeⅠprocollagen synthesis,Rb1,Rh2 and compound K were active.Among them, compound K was the most active compound.The typeⅠprocollagen,which was treated with compound K, was found to be 114.8%.In inhibition of MMP-1,Rb1,Rc,Rd and compound K were active.In case of MMP-1 inhibition,compound K was also most active compound.From these results,we suggest that compound K may be used as a good candidate for the treatment of skin aging.

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