Over-expression of annexin 1 inhibits LPS-induced inflammatory reactions in mice
【摘要】:正Annexin 1 (ANX1) is a calcium-dependent phospholipid-binding protein exhibiting anti- inflammatory activity. To elucidate the role of ANX1 in inflammation, we established transgenic mice (Tg) that over-express human ANX1. Kinetic analysis revealed that infiltration of neutrophils to an inflammatory tissue was significantly
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