收藏本站
收藏 | 手机打开
二维码
手机客户端打开本文

Study of the appropriate surgical procedure for early stage endometrial carcinoma

【摘要】:正Objective To study the appropriate surgical procedure for early stage endometrial carcinoma,the clinical,pathological features and prognosis factors as well as types were analyzed retrospectively.Methods This is a retrospective study of 277 patients with early stage endometrial carcinoma in clinical stagesⅠandⅡwho received surgery in our hospital between Jan.2000 and Mar.2011.The appropriate surgical procedures were divided into three types according to the clinical stage(procedureⅠhysterectomy,procedureⅡradical or modified radical hysterectomy with pelvic lymph node biopsy or sampling,procedureⅢradical hysterectomy or modified radical hysterectomy with pelvic lymphadenectomy).We analyzed the different stages after falling ill,highrisk factors,pathologic types,grades and prognosis factors.Results 1.Tumor invasion of the cervix and deep muscularis as well as the parametrium,endometrial carcinoma stagⅡgrade 3 and ascites had carcinoma cells,and a significantly raised Cal25 blood test(P 0.05) were high-risk factors of endometrial carcinoma metastasis to the parametrium and ovaries.2.Tumor invasion of the cervix and deep muscularis as well as the parametrium,endometrial carcinoma stage n,grade 3 and ascites had carcinoma cells,were high-risk factors of endometrial carcinoma metastasis to the retroperitoneum(P0.05).A positive ER/PR was not correlated significantly to retroperitoneum or lymph node metastatasis.3.The type of procedure for the endometrial carcinoma stage la was not correlated significantly to the 3-year and 5-year survival rates.The survival rates of operation proceduresⅡandⅢwere significantly higher than that for procedureⅠ(P 0.05).The survival rates after surgical proceduresⅡandⅢwere not significantly correlated.The 3-year and 5-year survival rates of surgical proceduresⅠ,ⅡandⅢwere significantly correlated(P 0.05) and significantly higher for procedureⅢthan those of proceduresⅠandⅡ.4.The 3-year survival rate was not correlated significantly to postoperative chemotherapy and radiotherapy or hormone treatment. The 5-year survival rate was significantly higher than that without postoperative chemother- apy and radiotherapy or hormonal therapy(P0.05).Conclusion 1.At the endometrial carcinoma stage Ia,any young patient who received hysterectomy and kept her ovaries was not discovered metastatic tumor at follow-up.2.Radical hysterectomy or modified radical hysterectomy was used for endometrial carcinoma stage Ib with high-risk factors.3.Radical hysterectomy or modified radical hysterectomy with pelvic and paraaortic lymphadenectomy was used for endometrial carcinoma stage Ic andⅡ.4.According to the postoperative pathologic diagnosis and immunohistochemistry results,radiotherapy and chemotherapy as well as an adjuvant hormonal treatment should be used in cases with high-risk factors.

知网文化
【相似文献】
中国重要会议论文全文数据库 前9条
1 ;Study of the appropriate surgical procedure for early stage endometrial carcinoma[A];中国抗癌协会妇科肿瘤专业委员会第十一届全国学术会议论文汇编[C];2011年
2 ;Clinical significance of IEX-1 expression in ovarian carcinoma[A];2011中国妇产科学术会议暨浙江省计划生育与生殖医学学术年会暨生殖健康讲习班论文汇编[C];2011年
3 ;Reduced expression of △Np63α in cervical squamous cell carcinoma[A];“细胞活动 生命活力”——中国细胞生物学学会全体会员代表大会暨第十二次学术大会论文摘要集[C];2011年
4 ;Transcervical Suction of Interstitial Pregnancy under Laparoscopic and Hysteroscopic Guidance[A];创新创业与科学发展——瑞安市第十届自然科学优秀论文集[C];2011年
5 ;The value of 3D Power Doppler to predict clinical and histological response to neoadjuvant chemotherapy in locally advanced cervical carcinoma[A];2011年浙江省超声医学学术年会论文汇编[C];2011年
6 杨英捷;;妇科内镜在辅助生育技术的应用[A];贵州省生殖医学与遗传学分会2010年第二届年会论文集[C];2010年
7 ;Expression of BMI-1 in human cervical tissue-a diagnostic and prognosis marker in patients with uterine cervical cancer[A];中华医学会第九次全国检验医学学术会议暨中国医院协会临床检验管理专业委员会第六届全国临床检验实验室管理学术会议论文汇编[C];2011年
8 杨艳峰;许泓;周彩云;黄秀峰;张信美;林俊;;RANTES及其受体CCR1和雌激素受体亚型(ER-alpha/ER-beta)在子宫腺肌病中的表达[A];2011中国妇产科学术会议暨浙江省计划生育与生殖医学学术年会暨生殖健康讲习班论文汇编[C];2011年
9 ;Expression and Clinical Significance of Phosphatidyl inositol 3-kinase in Cervical Carcinoma[A];2011中国妇产科学术会议暨浙江省计划生育与生殖医学学术年会暨生殖健康讲习班论文汇编[C];2011年
中国博士学位论文全文数据库 前10条
1 陈宁;Nrf2参与子宫内膜浆液性癌发病及耐药机制的研究[D];山东大学;2011年
2 吴飞;性激素对子宫内膜癌细胞增殖、侵袭、凋亡的影响及术后HRT安全性循证医学分析[D];吉林大学;2011年
3 张广华;子宫内膜癌细胞孕激素受体基因表观遗传学调控的研究-DNA甲基化及表达沉默相关的染色质成分变化[D];天津医科大学;2010年
4 贾赞慧;重组蛋白IGF-1α对子宫内膜癌细胞Ishikawa增殖作用的研究[D];吉林大学;2010年
5 邓新超;子宫内膜癌组织中DACH1基因启动子的甲基化状态及其临床意义[D];山东大学;2012年
6 李莉;蛋白质组学技术对胃癌、肝癌、卵巢癌血清差异蛋白表达的研究[D];新疆医科大学;2011年
7 石敏;正常子宫内膜间质细胞对子宫内膜腺癌细胞存活与凋亡的调节[D];山东大学;2011年
8 卢永超;SK3在早期胚胎发育、子宫内膜生长及子宫内膜癌发病中的作用研究[D];浙江大学;2011年
9 梁淑美;ALCAM在子宫内膜恶性转化中的作用[D];山东大学;2011年
10 刘洋;姜类萜类化合物激活P53信号通路诱导子宫内膜细胞凋亡研究[D];山东大学;2013年
中国硕士学位论文全文数据库 前10条
1 盛少琴;子宫内膜间质肉瘤37例临床分析[D];浙江大学;2010年
2 丁兰芳;雌激素通过激活AKT诱导产生癌基因因子的研究[D];广西医科大学;2010年
3 胡月;子宫内膜癌腹主动脉旁淋巴结切除术临床意义的Meta分析[D];山东大学;2013年
4 李艳;子宫浆液性乳头状癌14例临床分析[D];大连医科大学;2010年
5 董冰;应用3.0T MR 3D LAVA动态增强与DWI检查评估子宫内膜癌分期与分级[D];天津医科大学;2012年
6 刘晓旭;ACT、INH、p16和p53在子宫内膜癌中的表达及意义[D];中南大学;2010年
7 王丽君;瘦素对人子宫内膜癌细胞雌激素原位合成的影响[D];辽宁医学院;2011年
8 郝曼;子宫内膜癌治疗的新进展[D];兰州大学;2012年
9 李蕾;子宫内膜浆液性乳头状癌的诊治进展[D];蚌埠医学院;2012年
10 陈剑;磁共振成像作为辅助技术对子宫内膜癌临床分期的探讨[D];山东大学;2011年
 快捷付款方式  订购知网充值卡  订购热线  帮助中心
  • 400-819-9993
  • 010-62982499
  • 010-62783978