Cell-free miRNAs may indicate diagnosis and docetaxel sensitivity of tumor cells in malignant effusions

【摘要】：正Tyrosine phosphorylation plays a key role in cellular processes such as cell proliferation,differentiation,metabolism,cellto -cell communication,gene transcription,and survival.This rapidly reversible process is determined by a balance between the activities of protein tyrosine kinases(PTKs) and protein tyrosine phosphatases(PTPs).Whereas PTKs transmit signals by a cascade of phosphorylation events,PTPs that can dephosphorylate the kinases can modulate the intensity and