【摘要】:正β-Amino-α,α-difluorocarbonyl compoundsare useful intermediates in organic synthesis and medicinal chemistry,as the incorporation of gem-difluoromethylene groupoften enhanceselectrophiHcity,acidity and lipophilicity of its neighboring group.A fewmethods have been developed forthe diastereoselectivesynthesis ofβ-amino-α,α-difluoro carbonyl compounds includingReformatsky reaction,
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