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Masamitsu Honma  
【摘要】:正The International Conference on Harmonization of Technical Requirements for Registration of Pharmaceutical for Human Use(ICH) has started a revision of the genotoxicity guidance (S2A and S2B) from 2006.The current genotoxicity guidance documents were adopted in 1995(S2A) and 1997(S2B).During the last decade,there have been new developments and a


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