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Discovery of Tylophorine Derived Dibenzoisoquinoline Compounds for Anti-inflammation

Yue-Zhi Lee  Cheng-Wei Yang  Shiow-Ju Lee  
【摘要】:正Inflammation is mediated by a variety of soluble factors and cellular signaling events.Phenanthroindolizidines and phenanthroquinolizidines are structure-related alkaloids.Tylophorine and cryptopleurine are respective representatives of the two classes of alkaloids.Tylophorine is believed to account for the anti-inflammation-related effects of Tylophora indica.

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