【摘要】：正For almost all sorts of analytical methods,the dream to improve their sensitivity as well as their reproducibility and to make the detected signals cleaner is a long-term pursuit.Since its discovery in the 1970s,surface enhanced Raman spectroscopy(SERS) has shown potential applications in the ultrasensitive characterization of many materials down to the single molecule level.However,existing SERS methods usually give distorted and irreproducible results and thus practical applications are often hindered(Fig 1 A).