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The R219K polymorphism in the A TP-binding cassette transporter 1 gene has a protective effect on atherothrombotic cerebral infarction in Chinese Han ethnic population

王柠  薛偕华  林毅  方玲  慕容慎行  吴志英  
【摘要】:正Objective The association of R219K and V825I polymorphisms of ABCA1 gene with cerebral infarction has been rarely reported. Here we wish to address this issue. Methods A total of 476 subjects from Chinese Han eth- nic population were investigated, including 152 control individuals and 324 patients with cerebral infarction. Geno- typing of R219K and V825I was performed by PCR-RFLP analysis. Fasting blood samples of all subjects were

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