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Structural insights into the sequential O-glycosylation and molecular function of serine-rich repeat proteins

Yong-Liang Jiang  Yi-Hu Yang  Wei-Wei Shi  Hua Jin  Rong-Li Zhao  Yuxing Chen  Cong-Zhao Zhou  
【摘要】:正The serine-rich repeat proteins(SRRPs)are a large family of surface adhesins in Gram-positive bacteria.They are crucial for bacterial adhesion,immune evasion,colonization,biofilm formation and virulence.The serine-rich repeat regions of SRRPs are usually subject to O-glycosylation for increasing the mobility and stability of nascent SRRPs.O-glycosylation is an

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