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Structural Reconfiguration during the yeast 26S proteasome assembly

Xueming Li  
【摘要】:正The proteasomal ATPase ring,comprising Rpt1-Rpt6,associates with the heptamericαring of the proteasome core particle(CP)in the mature proteasome,with the Rpt C-terminal tails inserting into pockets of theαring.This work clarified the debates about the specificities of Rpt C-termini and found the special role of Rpt6 C-terminus in 26S complex assembling.By Electron cryomicroscopy(cryoEM),we observed

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