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A Bioinspired Platform for Effective Delivery of Protein Therapeutics to the Central Nervous System

Di Wu  Meng Qin  Duo Xu  Lan Wang  Chaoyong Liu  Jie Ren  George Zhou  Chen Chen  Fengmei Yang  Yanyan Li  Yuan Zhao  Ruyi Huang  Sina Pourtaheri  Chunsheng Kang  Masakazu Kamata  Irvin S.Y.Chen  Zhanlong He  Jing Wen  Wei Chen  Yunfeng Lu  
【摘要】:正Central nervous system (CNS) diseases are the leading cause of morbidity and mortality;their treatment,however,remains constrained by the blood–brain barrier (BBB) that impedes the access of most therapeutics to the brain.A CNS delivery platform for protein therapeutics,which is achieved by encapsulating the proteins

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