A Bioinspired Platform for Effective Delivery of Protein Therapeutics to the Central Nervous System

Di Wu Meng Qin Duo Xu Lan Wang Chaoyong Liu Jie Ren George Zhou Chen Chen Fengmei Yang Yanyan Li Yuan Zhao Ruyi Huang Sina Pourtaheri Chunsheng Kang Masakazu Kamata Irvin S.Y.Chen Zhanlong He Jing Wen Wei Chen Yunfeng Lu

【摘要】：正Central nervous system (CNS) diseases are the leading cause of morbidity and mortality;their treatment,however,remains constrained by the blood–brain barrier (BBB) that impedes the access of most therapeutics to the brain.A CNS delivery platform for protein therapeutics,which is achieved by encapsulating the proteins

下载App查看全文

下载全文更多同类文献

PDF全文下载

CAJ全文下载

(如何获取全文？欢迎：购买知网充值卡、在线充值、在线咨询)

CAJViewer阅读器支持CAJ、PDF文件格式，AdobeReader仅支持PDF格式

	【相似文献】
	【相似文献】

中国期刊全文数据库

前20条

1	Lin Lei;Rongshou Zheng;Ke Peng;Lei Si;Ji Peng;Weicong Cai;Siwei Zhang;Wenqiang Wei;Jie He;;Incidence and mortality of oral and oropharyngeal cancer in China, 2015[J];Chinese Journal of Cancer Research;2020年01期
2	Gary Yee Ang;;Age of onset of diabetes and all-cause mortality[J];World Journal of Diabetes;2020年04期
3	Colum Downey;Martin Kelly;John F Quinlan;;Changing trends in the mortality rate at 1-year post hip fracture-a systematic review[J];World Journal of Orthopedics;2019年03期
4	ZHENG Jing;TONG Chang-qing;ZHANG Gui-jun;;Modeling stochastic mortality with O-U type processes[J];Applied Mathematics:A Journal of Chinese Universities;2018年01期
5	孙妍蓓;;Effect of acute kidney injury on short-and long-term mortality of patients with acute myocardial infarction[J];China Medical Abstracts(Internal Medicine);2017年01期
6	Su-Hsin Huang;Joon-Khim Loh;Jinn-Tsong Tsai;Ming-Feng Houg;Hon-Yi Shi;;Predictive model for 5-year mortality after breast cancer surgery in Taiwan residents[J];Chinese Journal of Cancer;2017年04期
7	Ke-Peng Xin;Mao-Lin Du;Zhi-Yue Liu;Wen-Rui Wang;Yong-Gang Qian;Li Liu;Yun-Fei Lv;Juan Sun;;Colorectal cancer mortality in Inner Mongolia between 2008 and 2012[J];World Journal of Gastroenterology;2014年25期
8	;Community Health[J];现代护理;2004年09期
9	吴启运,王才成,黄晓华,康庶,孙文广,冯亚飞,夏觉中;Treatment of 116 patients with severe craniocerebral injury in basic-level hospital[J];Chinese Journal of Traumatology;2003年03期
10	Peizhong Peter Wang;;Regional variations in mortality rates of pancreatic cancer in China:Results from 1990-1992 national mortality survey[J];World Journal of Gastroenterology;2003年11期
11	;Study of relationship between pulse pressure and mortality from all the causes, CVD and CVA[J];泰山医学院学报;2002年04期
12	陈惠金,吴圣楣,黄萍,孙建华,陈冠仪,储凇雯;PHENOBARBITAL FOR THE PREVENTION OF IVH INCHINESE PREMATURE INFANTS[J];Journal of Shanghai Second Medical University;1999年01期
13	Chang Pan;Xiao-ran Huang;Jiao-jiao Pang;Kai Cheng;Feng Xu;Yu-guo Chen;;Trends in mortality of emergency departments patients in China[J];World Journal of Emergency Medicine;2019年03期
14	胡玉刚;;Incidence and mortality of acute kidney injury in coronary care unit:a retrospective study from a single center[J];China Medical Abstracts(Internal Medicine);2017年02期
15	Lekha Saha;Narinder Kumar;Pratibha Khosla;Sharonjeet Kaur;;Role of statin on mortality outcome in pneumonia patients: A meta-analysis[J];World Journal of Meta-Analysis;2014年03期
16	;Impact of change in serum sodium concentration on mortality in patients hospitalized with heart failure and hyponatremia[J];South China Journal of Cardiology;2011年03期
17	Liu Tongtong;;Life Table of Natural Population of Gastrolina depressa[J];Plant Diseases and Pests;2020年03期
18	Rui-xue Sun;Priscilla Song;Joseph Walline;He Wang;Ying-chun Xu;Hua-dong Zhu;Xue-zhong Yu;Jun Xu;;Morbidity and mortality risk factors in emergency department patients with Acinetobacter baumannii bacteremia[J];World Journal of Emergency Medicine;2020年03期
19	Prapaipan Putthapiban;Wasawat Vutthikraivit;Pattara Rattanawong;Weera Sukhumthammarat;Napatt Kanjanahattakij;Jakrin Kewcharoen;Aman Amanullah;;Association of frailty with all-cause mortality and bleeding among elderly patients with acute myocardial infarction: a systematic review and meta-analysis[J];Journal of Geriatric Cardiology;2020年05期
20	Shuzheng Liu;Qiong Chen;Lanwei Guo;Xiaoqin Cao;Xibin Sun;Wanqing Chen;Jie He;;Incidence and mortality of lung cancer in China, 2008-2012[J];Chinese Journal of Cancer Research;2018年06期

中国重要会议论文全文数据库

前10条

1	Di Wu;Meng Qin;Duo Xu;Lan Wang;Chaoyong Liu;Jie Ren;George Zhou;Chen Chen;Fengmei Yang;Yanyan Li;Yuan Zhao;Ruyi Huang;Sina Pourtaheri;Chunsheng Kang;Masakazu Kamata;Irvin S.Y.Chen;Zhanlong He;Jing Wen;Wei Chen;Yunfeng Lu;;A Bioinspired Platform for Effective Delivery of Protein Therapeutics to the Central Nervous System[A];第十五届中国实验动物科学年会论文集[C];2019年
2	邓继祥;Hu X;Xiao C;Xu S;Gao X;Ma Y;Yang J;Wu M;Liu X;Ni J;Pan F;;Ambient temperature and non-accidental mortality:a time series study[A];安徽省2019年度流行病与卫生统计学学术年会论文集[C];2019年
3	Yu-bao Qiu;Chen Wu;Xue-qian Sun;Dan Chen;Jun-liang Chen;Ya-xian Wu;Qing-feng Pang;;Roles of platelet count and leukocyte count in predicting mortality in patients with severe burns[A];第七届全国呼吸系统重大疾病转化医学学术论坛论文汇编[C];2019年
4	Hai Yu;Mengjia Gu;Yingjun Li;Mingjuan Jin;Jianbing Wang;Kun Chen;;Sedentary behaviors and all-cancer mortality:A systematic review and meta-analysis[A];全国肿瘤流行病学和肿瘤病因学学术会议论文集[C];2015年
5	Yingjun Li;Mengjia Gu;Mingjuan Jin;Jianbing Wang;Kun Chen;;Sedentary behaviors and all-cancer mortality:A systematic review and meta-analysis[A];2014浙江省临床流行病学与循证医学学术年会论文汇编[C];2014年
6	Yunquan Zhang;Chuanhua Yu;;Association of diurnal temperature range with mortality in England and Wales:A nationwide time-series study[A];2017年中国卫生统计学学术年会论文集[C];2017年
7	王建炳;顾梦佳;林鸿波;沈鹏;鲍成臻;叶臻华;王悠清;Mamat Mayila;叶丁;顾石桐;陈坤;;Body Mass Index and mortality in Chinese men and women[A];2015浙江临床研究大会暨浙江省临床流行病学与循证医学学术年会资料汇编[C];2015年
8	Yingjun Li;Mengjia Gu;Chengzhen Bao;Jianbing Wang;Mingjuan Jin;Kun Chen;;Association between physical activity and all cancer mortality:Doseresponse meta-analysis of cohort studies[A];2015浙江临床研究大会暨浙江省临床流行病学与循证医学学术年会资料汇编[C];2015年
9	Zhenhua Xu;Ruida Zhu;Chao Liu;;The effect of mortality salience on the neurocognitive processing of guilt and shame[A];第二十一届全国心理学学术会议摘要集[C];2018年
10	Junying Zhou;Jihui Zhang;Yun Kwok Wing;;Mortality and Its Risk Factors in Patients with Rapid Eye Movement Sleep Behavior Disorder[A];中国睡眠研究会第九届学术年会汇编[C];2016年

中国博士学位论文全文数据库

前1条

1	Khadim Hussain Memon;[D];中国海洋大学;2014年

中国硕士学位论文全文数据库

前2条

1	Blessing Tinashe Manzou;[D];浙江科技学院;2019年
2	杨军;广州市气象因素对居民死亡影响的研究[D];南方医科大学;2013年

	快捷付款方式		订购知网充值卡	订购热线	帮助中心
	微信支付支付宝银行卡	知网卡在线购卡更多>>	免费送卡上门银行汇款购卡邮局汇款购卡	400-819-9993 010-62982499 010-62783978	常见问题在线咨询阅读器下载	充值中心知网卡新手指南