The effects of maternal rats exposed to chronic unpredictable stress and fluoxetine treatmnet before pregnancy on the behavior and neurobiology of themselvs and their progeny

【摘要】：正Background Maternal stress or depression has a negative impact on the behavior and is linked to an increased risk for affective disorders in their progeny.Follow-up on the progeny of depressed and non-depressed parents shows that parental depression is a strong and consistent risk factor for progeny's major depression disorder and anxiety disorders. And substance dependence in the progeny of depressed parents are about three times as high as that in the progeny of