Expression and Clinical Significance of Phosphatidyl inositol 3-kinase in Cervical Carcinoma
【摘要】:正Background Phosphatidylinositol 3-kinase / protein kinase B(PI3K/Akt)signaling pathway is involved in variety of important cellular function,which also intimately relates to the genesis and progression of neoplasm.However,its role in the cervical cancer is unclear.This study was to detect the expression of PI3K protein in different cervical lesions and to investigate the correlation of PI3K/Akt signal transduction pathway to biological behavior of cervical carcinoma.