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Anoxic preconditioning prevents anoxia/reoxygenation-induced apoptosis in neonatal rat cardiomyocytes via up-regulation of 14-3-3 protein

【摘要】:正Anoxic preconditioning(APC)attenuates myocardial injury caused by anoxia /reoxygenation(A/R).The protective mechanisms of APC involve up-regulation of the protective proteins and inhibition of apoptosis.14-3-3 protein,as a molecular chaperone,plays an important role in regulating cell survival and apoptosis.However, it remains unknown whether 14-3-3 protein is up-regulated in the setting of APC and

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