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《第五届全国人畜共患病学术研讨会论文摘要集》2017年
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NDV V protein disrupts innate immunity by degrading Mitochondrial Antiviral Signaling Protein

丁铲  
【摘要】:正Newcastle disease virus(NDV)is a single-stranded,nonsegmented,negative-sense RNA virus which is able to infect most species of birds and cause highly contagious Newcastle disease.Similar to other viruses,NDV establishes an intimate and complex interaction with the host cell to counteract the antiviral responses elicited by the cell.Among various pattern recognition receptors(PAMPs)of the host,the cytosolic RNA helicases interact with viral RNA to activate the Mitochondrial Antiviral Signaling protein(MAVS),which regulates cellular interferon response.
【作者单位】:中国农科院上海兽医研究所
【分类号】:S852.65

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