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《第四届全国冷冻电子显微学与结构生物学专题研讨会论文集》2015年
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Atomic structure of anthrax PA pore elucidates toxin translocation

江健森  Bradley L.Pentelute  R.John Collier  Z.Hong Zhou  
【摘要】:正Anthrax toxin,comprising protective antigen(PA),lethal factor(LF)and edema factor(EF),is the major virulence factor of Bacillus anthracis,an agent that causes high mortality in humans and animals.PA forms oligomeric prepores that undergo conversion to membrane-spanning pores by endosomal acidification,and these pores translocate the
【作者单位】:University of California Massachusetts Institute of Technology Harvard Medical School
【分类号】:R378
【正文快照】:
Anthrax toxin,comprising protective antigen(PA),lethal factor(LF)and edema factor(EF),is the major virulence factor of Bacillus anthracis,an agent that causes highmortality in humans and animals.PA forms oligomeric prepores that undergo conversionto memb

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