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《第四届全国冷冻电子显微学与结构生物学专题研讨会论文集》2015年
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Structures of TRP ion channels by single particle cryo-EM

程亦凡  
【摘要】:正As a versatile tool in structural biology,single particle electron cryo-microscopy(cryo-EM)has been used to determine the three-dimensional(3D)structures of proteins and macromolecular complexes without the need for crystals.However,for many years,the achievable resolution of this technique,particularly for integral membrane proteins,was limited at nanometer to sub-
【作者单位】:The Keck Advanced Microscopy Laboratory,Department of Biochemistry and Biophysics University of California
【分类号】:Q617
【正文快照】:
As a versatile tool in structural biology,single particle electron cryo-microscopy(cryo-EM)hasbeen used to determine the three-dimensional(3D)structures of proteins and macromolecularcomplexes without the need for crystals.However,for many years,the achi

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