Genome-wide A-to-I RNA editing during sexual reproduction in filamentous ascomycetes

【摘要】：正Yeasts and filamentous fungi do not have Adenosine Deaminase Acting on RNA(ADAR)orthologs and are believed to lack A-to-I RNA editing,which is the most prevalent m RNA editing m RNA in animals.However,we recently found that A-to-I editing occurs specifically during sexual reproduction in the wheat scab fungus Fusarium graminearum.Genome-wide analysis identified 26,056 perithecium-specific A-to-I editing sites.Unlike those in animals,