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《中国抗癌协会神经肿瘤专业委员会第八届学术会议论文集》2011年
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Impact factor analysis of post-operation life quality according to KPS in adult supratentorial superficial low-grade glioma

【摘要】:Objective:We assessed the life quality of adult supratentorial superficial low-grade glioma(ASS-LGG) patients according to Karnofsky Performance Scale(KPS) and analyzed the relevant factors.Some benefit factors were found through this research to guide the therapeutic strategy and improve the patients' prognosis after glioma surgery.Method:One hundred and four adults with ASS-LGG were collected and analyzed retrospectively from 2008 to 2009.The follow-up time was from three months to half of a year.The logistic regression was used to discuss the relationship between the life quality after surgery according to KPS and the impact factors such as age,gender,operation time,size and location of the tumor,degree of resection,and tumor grade before surgery.Result:We found that four out of ten candidate factors have pertinence with the improvement of the life quality after surgery.They are age more than 40 years,the size of tumor less than 5cm,tumor located in the right hemisphere and limited resection of tumor in functional area.Conclusions:It's seems more significant to judge ASS-LGG patients' prognosis on the base of life quality because of the patients' long-time survival.To ASS-LGG patients,we could predict the life quality according to KPS after surgery depending on the patients' age,and size and location of the tumor.It is benefit to the improvement of life quality if the tumor is resected at early stage.Relieving the size of the tumor and acquiring the pathological diagnosis should be recommended instead of the en bloc resection in functional area.
【分类号】:R739.41

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