Development of a Web-Based Laboratory Class to Reduce the Challenges in Teaching Fragment-Based Drug Design
【摘要】：Fragment-based drug design(FBDD) is a promising methodology to find quality drug leads. It is important in the curriculum of a drug design course due to its impact on drug discovery. However, teaching FBDD and its use by students remain challenging in most cases. A web-based laboratory class to teach FBDD in the form of our copyrighted workshops is described. The students' feedback and a quantitative evaluation of the results show that the web-based laboratory class is popular with students and facilitates students' learning of FBDD for design of possible drug-like molecules. The web-based laboratory class provides an opportunity for students to experience the process of FBDD and to conceive drug-like molecules.