收藏本站
收藏 | 手机打开
二维码
手机客户端打开本文

Bacterial lipopolysaccharide core structures mediate effects of butanol ingress

郭晶晶  
【摘要】:The outer membrane(OM) is the first defence for Gram-negative bacteria against their environments making it important in strain improvement for sustainable biobutanol production1-2. While modifying the OM structure using chemical additives could enhance microbial viability, there are currently no model systems that accurately describe OM responses to butanol. Here, we experimentally determined that reducing the lipopolysaccharide(LPS) core length and charge increased Escherichia coli sensitivity to butanol. In silico models were built to describe how OM structure contributes to its ability to withstand butanol under conditions of exposure and production. Consistent with experiments, resistance to ingress of butanol into OMs correlates with both core length and charge, where a lower charge density is more conducive to butanol assimilation. The core length and branching correlate with the lateral spacing of the lipids, suggestive of a role of them in maintaining OM fluidity. In contrast to systems with short-length LPS cores, butanol intercalation into OMs with longer LPS cores increases membrane order and rigidity, which might be due to their more porous internal structure. These findings will assist the development of more butanol-tolerant biobutanol-producing bacteria, where thicker, more compact and less polar LPS-core surfaces reinforce the integrity of OMs and further improve resilience in extreme environments.

知网文化
【相似文献】
中国期刊全文数据库 前20条
1 Yanjun WANG;Jianming ZHAN;Xinhua XU;Lishuai LI;Ping CHEN;Mark HANSEN;;Measuring the resilience of an airport network[J];Chinese Journal of Aeronautics;2019年12期
2 Ke Cui;Ziqiang Han;;Cross-Cultural Adaptation and Validation of the 10-Item Conjoint Community Resiliency Assessment Measurement in a Community-Based Sample in Southwest China[J];International Journal of Disaster Risk Science;2019年04期
3 ;China's Economy Remains Resilient Amid Epidemic Outbreak: Report[J];China's Foreign Trade;2020年01期
4 A.M.Aslam Saja;Melissa Teo;Ashantha Goonetilleke;Abdul M.Ziyath;K.W.G.Rekha Nianthi;;Surrogate Measures to Assess Mobility of People as a Resilience Indicator in Disaster Management: An Exploratory Study in Southeastern Sri Lanka[J];International Journal of Disaster Risk Science;2020年01期
5 Jing LI;Shaoyu TONG;;Effect of Land Use on Flood Resilience[J];Asian Agricultural Research;2020年04期
6 Xiaozhai Qi;George C.Lee;;From the editors[J];Earthquake Engineering and Engineering Vibration;2020年03期
7 Ghazanfar Ali Anwar;You Dong;;Seismic resilience of retrofitted RC buildings[J];Earthquake Engineering and Engineering Vibration;2020年03期
8 Gianluca Pescaroli;Omar Velazquez;Irasema Alcántara-Ayala;Carmine Galasso;Patty Kostkova;David Alexander;;A Likert Scale-Based Model for Benchmarking Operational Capacity,Organizational Resilience,and Disaster Risk Reduction[J];International Journal of Disaster Risk Science;2020年03期
9 Lei Lyu;Ling-Yan Xu;Min Liu;Guo-Hong Li;;Resilience in new nurses:a qualitative study[J];Frontiers of Nursing;2020年02期
10 Shang Qingxue;Guo Xiaodong;Li Quanwang;Xu Zhen;Xie Linlin;Liu Chaofeng;Li Jichao;Wang Tao;;A benchmark city for seismic resilience assessment[J];Earthquake Engineering and Engineering Vibration;2020年04期
11 Xiaozhai Qi;George C.Lee;;From the editors[J];Earthquake Engineering and Engineering Vibration;2020年04期
12 Yang Cantian;Xie Linlin;Li Aiqun;Zeng Demin;Jia Junbo;Chen Xi;Chen Min;;Resilience-based retrofitting of existing urban RC-frame buildings using seismic isolation[J];Earthquake Engineering and Engineering Vibration;2020年04期
13 FENG Xinghua;LEI Jing;XIU Chunliang;LI Jianxin;BAI Limin;ZHONG Yexi;;Analysis of Spatial Scale Effect on Urban Resilience:A Case Study of Shenyang, China[J];Chinese Geographical Science;2020年06期
14 Dragan Komljenovic;Lazar Stojanovic;Vladimir Malbasic;Aleksandar Lukic;;A resilience-based approach in managing the closure and abandonment of large mine tailing ponds[J];International Journal of Mining Science and Technology;2020年05期
15 REN Xurui;;A Comparative Study on Urban Ecological Resilience in the Pearl River Delta Region[J];Journal of Landscape Research;2019年02期
16 PAN Xing;WANG Huixiong;YANG Yanjing;ZHANG Guozhong;;Resilience based importance measure analysis for SoS[J];Journal of Systems Engineering and Electronics;2019年05期
17 Shiyuan WANG;Payman DEHGHANIAN;Mohannad ALHAZMI;Mostafa NAZEMI;;Advanced control solutions for enhanced resilience of modern power-electronic-interfaced distribution systems[J];Journal of Modern Power Systems and Clean Energy;2019年04期
18 Hieu T.NGUYEN;John W.MUHS;Masood PARVANIA;;Assessing impacts of energy storage on resilience of distribution systems against hurricanes[J];Journal of Modern Power Systems and Clean Energy;2019年04期
19 Herman van Wietmarschen;Yan Schroёn;Victor Kallen;Marvin Steijaert;Albert A.de Graaf;Ben van Ommen;Jan van der Greef;;Systems biology of resilience and optimal health:integrating Chinese and Western medicine perspectives[J];World Journal of Traditional Chinese Medicine;2017年01期
20 Omar Kammouh;Ali Zamani Noori;Veronica Taurino;Stephen A.Mahin;Gian Paolo Cimellaro;;Deterministic and fuzzy-based methods to evaluate community resilience[J];Earthquake Engineering and Engineering Vibration;2018年02期
中国重要会议论文全文数据库 前20条
1 Weiqi Sun;Yuanlong Li;Liangren Shi;;The Performance Evaluation and Resilience Analysis of Supply Chain Based on Logistics Network[A];第三十九届中国控制会议论文集(5)[C];2020年
2 郭晶晶;;Bacterial lipopolysaccharide core structures mediate effects of butanol ingress[A];2019中国化学会第十五届全国计算(机)化学学术会议论文集[C];2019年
3 Mathias V.Schmidt;;Ramping up stress resilience through inhibition of the cochaperone FKBP51[A];中国神经科学学会第十二届全国学术会议论文集[C];2017年
4 Miao-Jin JI;Xiao-Yang ZHANG;Zi CHEN;Jian-Jun WANG;Jing-Ning ZHU;;Orexin induces antidepressant-like effects via promoting resilience to acute stress[A];中国神经科学学会第十二届全国学术会议论文集[C];2017年
5 ;Resilience as a Predictor of Internet Addiction:The Mediation Effects of Perceived Class Climate and Alienation[A];Proceedings 2010 IEEE 2nd Symposium on Web Society[C];2010年
6 Tao Lili;Xu Zhiliang;Han Jing;Chen Jie;Zhang Hui;Cao Weiguo;;Copper-Catalyzed Cyclization/Oxidation/Aromatization Cascade:Efficient Synthesis of Trifluoromethylated Pyrrolo[2,1-a]isoquinolines[A];中国化学会第十三届全国有机合成化学学术研讨会论文摘要集[C];2016年
7 Shuanghong Chen;Todd Jackson;;Pain Beliefs Mediate Associations Between Resilience and Overall Functioning Among Adults with Chronic Back Pain: A Structural Equation Modeling Study[A];第二十届全国心理学学术会议--心理学与国民心理健康摘要集[C];2017年
8 ;Nonequilibrium Stability and Rosilience Measurements in Ecological Systems[A];第四届全国网络科学学术论坛暨研究生暑期学校论文集[C];2008年
9 Liang Shi;Jiangzhou Sun;Jiang Qiu;;Recover from the adversity:Functional connectivity basis of psychological resilience[A];第二十一届全国心理学学术会议摘要集[C];2018年
10 Xiujuan Feng;Di Zhao;Ping Li;;Hope and resilience contribute to lighter symptom burden among postsurgical head and neck cancer survivors :A structural equation model analysis[A];第二十一届全国心理学学术会议摘要集[C];2018年
11 ;The minimum dissipation state of tokamak plasmas with non-uniform resistivity[A];第十四届全国等离子体科学技术会议暨第五届中国电推进技术学术研讨会会议摘要集[C];2009年
12 TANG Xinyi;NIU Juan;RUAN Mingcheng;;Parents' educational involvement and psychology resilience as mediators between family socioeconomic status and class peer status of Chinese middle school students[A];第二十一届全国心理学学术会议摘要集[C];2018年
13 徐志平;;TEARING 2D MATERIALS:THE SELECTION OF FRACTURE PATTERNS[A];2018年全国固体力学学术会议摘要集(上)[C];2018年
14 Hongwei Wang;Minming Ni;Shigen Gao;Feng Bao;Haichuan Tang;;A Resilience-based Security Assessment Approach for Railway Signalling Systems[A];第37届中国控制会议论文集(E)[C];2018年
15 Li,S.;Ni,S.;Peng,K.;;Predict Resilience Level Based on Language Preference[A];第二十届全国心理学学术会议--心理学与国民心理健康摘要集[C];2017年
16 ;Network Construction for Fourth-Party Logistics based on Resilience with Using Particle Swarm Optimization[A];Proceedings of the 2011 Chinese Control and Decision Conference(CCDC)[C];2011年
17 Fu Yun;Zhao Hongli;Yang Haitao;;Research on The Static Robust and Vulnerability of Internet on The Level of Isp[A];2012年计算机应用与系统建模国际会议论文集[C];2012年
18 沈杰;张丽锦;;中小学生韧性量表的初步编制[A];全国教育与心理统计与测量学术年会暨第八届海峡两岸心理与教育测验学术研讨会论文摘要集[C];2008年
19 毛淑芳;李伟健;;复原力对自我复原的影响机制研究[A];第十一届全国心理学学术会议论文摘要集[C];2007年
20 Silin Huang;Mingyue Han;Ling Sun;;Family Socioeconomic Status and Emotional Adaption among rural-to-urban Migrant Children in China: The Moderating Roles of Children' Resilience and Parental Emotion[A];第二十届全国心理学学术会议--心理学与国民心理健康摘要集[C];2017年
中国博士学位论文全文数据库 前7条
1 阮思贤(Kate Nguyen);东西方文化背景下大学生故事讲述、价值观与心理弹性之间的关系研究[D];陕西师范大学;2015年
2 Life Professor Mashumba;[D];山东师范大学;2010年
3 胡寒春;青少年核心心理弹性的结构及其特征研究[D];中南大学;2009年
4 自山(Syed Zeeshan Mahfooz);[D];复旦大学;2011年
5 席居哲;基于社会认知的儿童心理弹性研究[D];华东师范大学;2006年
6 王东升;中学体育教师职业韧性研究[D];福建师范大学;2012年
7 同雪莉;留守儿童抗逆力生成研究[D];南京大学;2016年
中国硕士学位论文全文数据库 前20条
1 Dolores G. Perez Orozco;散货海港泊位分配及装卸设备调度协同优化研究[D];上海交通大学;2018年
2 RACQUEL SHANICE GRIFFITH;健全的治理和小国的经济复原力:毛里求斯和巴巴多斯的例研究[D];浙江大学;2019年
3 孙二虎;《非政府组织在非洲的风险应变项目研究》(节选)翻译报告[D];四川外国语大学;2015年
4 Mafirakureva Showmore;[D];东华大学;2012年
5 李嘉佳;《通过公私合作加强社区抗灾力建设》(节选)翻译报告[D];四川外国语大学;2016年
6 黄海燕;基于参考临界的社区抗逆力水平研究[D];南京大学;2013年
7 吴嵩霖;“心理弹性”在中学德育中的价值与运用[D];东北师范大学;2013年
8 安婷婷;奖赏改善慢性应激诱导抑郁样行为发生的前额叶mRNA/microRNA表达谱研究[D];青岛大学;2020年
9 田佳;食管癌患者心理弹性影响因素及干预措施研究[D];山西医科大学;2016年
10 蒙思锐(Wimonsiri Saengkrod);泰国邦龙社区居民洪灾中的恢复能力研究[D];华中科技大学;2014年
11 王林翮;大学生心理弹性特点及其影响因素[D];新乡医学院;2016年
12 吕晓玲;安徽省长丰县留守儿童的心理复原力及其与忽视、应对方式关系的研究[D];安徽医科大学;2013年
13 何颖妍;《勇面脆弱:不一样的生活之道》(节选)翻译报告[D];广东外语外贸大学;2014年
14 韦海燕;大学生复原力的干预研究[D];上海师范大学;2009年
15 焦娜娜;社区老年人抗逆力现状及其影响因素研究[D];华北理工大学;2020年
16 李丹;心理学论文Global Perspectives on Resilience in Children and Youth英汉翻译实践报告[D];黑龙江大学;2016年
17 孔田甜;心理弹性及影响因素与创伤后应激障碍关系的研究[D];新疆医科大学;2013年
18 宋娟;优秀贫困大学生心理弹性的建构研究[D];华东师范大学;2007年
19 陈梦龙;跆拳道训练干预对初中生心理弹性改善的实验研究[D];山西大学;2020年
20 李玉;大学生英语学习韧性与学习适应性的关系研究[D];杭州电子科技大学;2020年
中国重要报纸全文数据库 前1条
1 易水;计算机专业时文选读(934)[N];计算机世界;2004年
中国知网广告投放
 快捷付款方式  订购知网充值卡  订购热线  帮助中心
  • 400-819-9993
  • 010-62982499
  • 010-62783978