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《中国化学会·2016全国多糖研讨会论文摘要集》2016年
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HH1-1 targets galectin-3 with anti-pancreatic cancer activity in vitro and in vivo via blocking galectin-3 associated signaling pathways

Yanli Yao  Wenfeng Liao  Zhengyun Du  Kan Ding  
【摘要】:正Pancreatic cancer is known as the"king of cancer",because of its difficulty to diagnose,high mortality,and less effective drug.In this study,we show function of a homogeneous polysaccharide from a traditional Chinese medicine,which is named HH1-1.In vitro experiments showed that HH1-1 has good anti-pancreatic cancer activity,without significant toxicity.HH1-1can significantly inhibit the formation of clones.Subsequently,Bx PC-3 cells xenografte model in
【作者单位】:Glycochemistry and Glycobiology Lab, Shanghai Institute of Materia Medica, Chinese Academy of Sciences Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences University of Chinese Academy of Sciences
【分类号】:R285
【正文快照】:
Pancreatic cancer is known as the"king of cancer",because of its difficulty to diagnose,highmortality,and less effective drug.In this study,we show function of a homogeneouspolysaccharide from a traditional Chinese medicine,which is named HH1-1.In vitro

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