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《中国化学会·2016全国多糖研讨会论文摘要集》2016年
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HH1-1 targets galectin-3 with anti-pancreatic cancer activity in vitro and in vivo via blocking galectin-3 associated signaling pathways

Yanli Yao  Wenfeng Liao  Zhengyun Du  Kan Ding  
【摘要】:正Pancreatic cancer is known as the"king of cancer",because of its difficulty to diagnose,high mortality,and less effective drug.In this study,we show function of a homogeneous polysaccharide from a traditional Chinese medicine,which is named HH1-1.In vitro experiments showed that HH1-1 has good anti-pancreatic cancer activity,without significant toxicity.HH1-1can significantly inhibit the formation of clones.Subsequently,Bx PC-3 cells xenografte model in

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