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《2018年第十二届中国药物制剂大会论文集》2018年
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Preparation of Total flavonoids nanosuspension from Viticis Fructus

任凤英  Bai Changcai  WANG Wen-ping  Liu Chen  
【摘要】:正The aim of this study was to prepare a nanosuspension of total flavonoids from Viticis Fructus by a combined method of deep eutectic solvent(DE)extraction and anti-solvent precipitation.Firstly,the DES of Choline chloride and 1.3-Butanediol(n/n,1/4)was used to extract total flavonoids and the extraction process was optimized using Box-Behnken design.(Fig1)The optimal conditions were determined as follows:the

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