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Radix Polygalae Enhances Autophagy and Accelerates the Degradation of Mutant Aggregated Proteins In Vitro

An-Guo Wu  Vincent Kam-Wai Wong  Su-Wei Xu  Wai-Kit Chan  Liang Liu  Betty Yuen-Kwan Law  
【摘要】:正Increasing number of researches have revealed the protective roles of autophagy in modulating neurodegenerative diseases through accelerating the clearance of aggregate-prone or mutant proteins in cells.In this study,we therefore set out to identify novel autophagy inducers from 150 different kinds of Chinese medicinal herbs,which may serve as

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1 ;Comparison of protocatechuic aldchyde in Radix Salvia miitiorrhiza and corresponding pharmacological sera from normal and fibrotic rats by high performance liquid chromatography[J];World Journal of Gastroenterology;2006年14期
2 ;Dynamic Microwave-assisted Extraction of Flavonoids from Radix Scutellariae[J];Chemical Research in Chinese Universities;2007年02期
3 Jang Woo Shin;Myong Min Lee;Jin Young Son;Nam Heon Lee;Chong Kwan Cho;Won Kyu Chung;Jung Hyo Cho;Chang Gue Son;;Myelophil, a mixture of Astragali Radix and Salviae Radix extract, moderates toxic side effects of fluorouracil in mice[J];World Journal of Gastroenterology;2008年15期
4 ;Screening of active fractions from Radix of Actinidiae chinensis in vitro[J];中国现代医学杂志;2011年06期
5 于华芸;王世军;滕佳林;季旭明;吴智春;马清翠;付先军;;Effects of Radix Aconiti Lateralis Preparata and Rhizoma Zingiberis on Energy Metabolism and Expression of the Genes Related to Metabolism in Rats[J];Chinese Journal of Integrative Medicine;2012年01期
6 ;Research Status of Astragali Radix on Nerve Cells and Nerve System Diseases[J];Chinese Herbal Medicines;2012年04期
7 Ruihua ZHANG;Yahui CUI;Yanchun ZHENG;Yana SUN;Yi ZHANG;Yuesu ZHANG;;Analysis on Chemical Constituents of Raw and Processed Radix Bupleuri[J];Medicinal Plant;2013年05期
8 Weiwei WANG;Yao CHEN;;Advances in Chemical Components and Pharmacological Actions of Radix Fici Simplicissae[J];Medicinal Plant;2013年09期
9 SUN Jie;JIANG Zhen-zuo;YAN Rui-qing;OLALEYE Olajide;ZHANG Xiao-long;CHAI Xin;WANG Yue-fei;;Quality Evaluation of Astragali Radix Products by Quantitative Analysis of Multi-components by Single Marker[J];Chinese Herbal Medicines;2013年04期
10 ZHAN Qin;ZHANG Feng;GAO Shou-Hong;CAI Fei;JIANG Bo;SUN Lian-Na;CHEN Wan-Sheng;;An HPLC-MS/MS method for the quantitative determination of platy-codin D in rat plasma and its application to the pharmacokinetics of Platycodi Radix extract[J];Chinese Journal of Natural Medicines;2014年02期
11 MENG Xiang-Long;GUO Xiao-Hui;CUI Nan-Nan;MA Jun-Nan;ZHANG Shuo-Sheng;FAN Zhou;;Pyrolysis characteristics of Radix Rhizoma Rhei, Cortex Moudan Radicis, and Radix Sanguisorbae and correlations with the carbonizing process of Chinese herbs[J];Chinese Journal of Natural Medicines;2014年01期
12 Xia LIU;Wei LI;Yechun DING;Xiaona FAN;;Determination of As,Hg,Se,Cd in Radix linderae by Hydride Generator-Atomic Fluorescence Spectrometry with Microwave Digestion[J];Medicinal Plant;2013年Z1期
13 Heping Huang;Shanlin Gao;Dianlei Wang;Peng Huang;Jincai Li;;Autotetraploidy induced in Nianmaohuangqin (Radix Scutellariae viscidulae) with colchicine in vitro[J];Journal of Traditional Chinese Medicine;2014年02期
14 Hong Wu;Niels Hфiby;Liang Yang;Michael Givskov;Zhijun Song;;Effects of Radix Ginseng on microbial infections: a narrative review[J];Journal of Traditional Chinese Medicine;2014年02期
15 刘树民;李玉洁;李淑莲;罗明媚;柳新林;王薇;;An Experimental Research into the Anti-aging Effects of Radix Arctii Lappae[J];Journal of Traditional Chinese Medicine;2005年04期
16 李敬;刘云海;方建国;陈新;谢委;;Effect of Radix Isatidis on the Expression of Moesin mRNA Induced by LPS in the Tissues of Mice[J];Journal of Huazhong University of Science and Technology(Medical Sciences);2007年02期
17 ;Radix Astragali-induced differentiation of rat bone marrow-derived mesenchymal stem cells[J];Neural Regeneration Research;2009年07期
18 ;Comparative analysis of essential oils found in Rhizomes Curcumae and Radix Curcumae by gas chromatography-mass spectrometry[J];Journal of Pharmaceutical Analysis;2011年03期
19 陶丽丽;雷燕;王国利;朱凌群;王洋;;Effect of Extracts from Radix Ginseng,Radix Notoginseng and Rhizoma Chuanxiong on Delaying Aging of Vascular Smooth Muscle Cells in Aged Rats[J];Chinese Journal of Integrative Medicine;2012年08期
20 肖碧英;毛淑杰;李先端;;Variations in the Composition of Fructus Evodiae after Processing with Radix Glycyrrhizae Extract[J];Chinese Journal of Integrative Medicine;2012年10期
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1 闻莹莹;;Fingerprint analysis of Radix fici hirtae by HPLC and LC-MS[A];中国化学会第27届学术年会第09分会场摘要集[C];2010年
2 ;Phytochemical diversity of Radix Scrophulariae and Environmental Influence[A];第九届全国药用植物及植物药学术研讨会论文集[C];2010年
3 ;Radix Astragali Suppresses Myocardial Inflammation and Improves Cardiac Function in Autoimmune Myocarditis Rats[A];2008心血管药理学术研讨会论文汇编[C];2008年
4 ;A new application of an aqueous diphase solvent system in one-step preparation of polysaccharide from the crude water extract of Radix Astragali by high-speed counter-current chromatography[A];中药与天然药高峰论坛暨第十二届全国中药和天然药物学术研讨会论文集[C];2012年
5 Quanfu Zheng;Yanling Zhao;Jiabo Wang;Xiaojiao Sun;Lei Jia;Jianyu Li;Limei Shan;Ruisheng Li;Honghong Liu;Ruilin Wang;Xueai Song;Yonggang Li;Xiaohe Xiao;;Microcalorimetry coupled with chemometric techniques for Toxicity evaluation of Radix Aconiti Lateralis Preparata(Fuzi) and its processed products on Escherichia coli[A];中国医药教育论坛-中国医药教育协会第三届三次理事大会暨学术年会论文专辑[C];2013年
6 孔维军;赵艳玲;山丽梅;肖小河;郭伟英;;Investigation of the Effect of Four Organic Acids in Radix Isatidis on E.coli Growth by Microcalorimetry[A];中华中医药学会第九届中药鉴定学术会议论文集——祝贺中华中医药学会中药鉴定分会成立二十周年[C];2008年
7 ;Coniferyl ferulate,isolated from Radix Angelicae sinensis,reverses multidrug resistance via strong inhibition of GST and down-regulation of P-glycoprotein[A];中药与天然药高峰论坛暨第十二届全国中药和天然药物学术研讨会论文集[C];2012年
8 Tiantian Liu;Yanling Zhao;Jiabo Wang;Xu Zhou;Zhiyong Sun;Quanfu Zheng;Ruisheng Li;Ping Zhang;Jianyu Li;Xueai Song;Xiaohe Xiao;;Action of crude Radix Aconiti Lateralis(Fuzi) and its processed products on splenic lymphocytes growth investigated by microcalorimetry[A];中国医药教育论坛-中国医药教育协会第三届三次理事大会暨学术年会论文专辑[C];2013年
9 ;Thermodynamic Study on Comparison of Antibacterial Effect among Different Extracts from Radix Isatis[A];中华中医药学会第九届中药鉴定学术会议论文集——祝贺中华中医药学会中药鉴定分会成立二十周年[C];2008年
10 xiangping kang;chao liang;guoqin jin;xueli zhang;zhangbin gong;weiwei dai;;Effects of Kidney-Tonifying Recipe on Neural Cell Apoptosis and Spatial Learning & Memory of Aging Rats[A];中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议论文集——专题报告七[C];2014年
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