Effect of nicotinamide mononucleotide on insulin secretion and gene expressions of PDX-1 and FoxO1 in RIN-m5f cells
【摘要】:正Objectives The aims of this study were to investigate the effects of Nampt on insulin secretion and gene expressions of PDX-1 and FoxO1 which were important transcription factors associated with insulin secretion. Materials and methods Insulin secretion level in RIN-m5f cells was detected by rat insulin ELISA detection kit.The mRNA expression levels of
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