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Idiopathic male infertility caused by CATSPER2 abnormality

Tao Luo  Hou-yang Chen  Qian-xing Zou  Tao Wang  Yi-min Cheng  Hua-feng Wang  Na Li  Shi-qi Weng  Xu-hui Zeng  
【摘要】:正CATSPER is the primary Ca~(2+)channel responsible for male fertility in mammalian spermatozoa.mainly supported by studies through CATSPER gene deletions in mice.However,the functional significance of CATSPER for human sperm fertilization remains largely unclear,majorly because of the unavailability of comparable gene manipulation on human.In this study,we identified an

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