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A homozygous frameshift FANCM mutation causes male infertility and atypical Fanconi anemia

Hao Yin  Qinghua Shi  
【摘要】:正Male infertility affects approximately 7%of men and presents most severely with spermatogenic failure.However,in majority of these cases,the underlying causes remain unknown.Here,we studied three infertile brothers,born to first-cousin parents.Two brothers were diagnosed with oligoasthenospermia and one with azoospermia.Whole exome sequencing and Sanger sequencing

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