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《第十二届全国生物力学学术会议暨第十四届全国生物流变学学术会议会议论文摘要汇编》2018年
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Mechanical responsive Lnc-DIF inhibits osteoblast differentiation via targeting mir-489-3p

Chong Yin  Ye Tian  Yan Zhang  Dijie Li  Lifang Hu  Zhihao Chen  Fan Zhao  Airong Qian  
【摘要】:正Objective Mechanical stimulation plays an important role during the process of skeletal system development and growth. As a new focus of mechanobiology, non-coding RNA takes an important part in regulating gene expression and biological functions under mechanical stimulation. However, its mechanism is still not clear. Methods For the purpose of discovering mechano-sensitive IncRNAs involved in osteogensis, we initiated characterization of IncRNAs by screening the expression levels of IncRNAs in random positioning machine treated me-

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